Ingredient

Histidine HCL

Neutral in 1

What is Histidine HCL?

Histidine HCL is a form of the amino acid histidine bound to hydrochloride for increased stability and absorption. Amino acids are building blocks of proteins and are crucial for various physiological processes.

In skincare products, histidine HCL is often used for its potential moisturizing properties and to support skin health. There is limited research on its topical effects, but it may help maintain the skin's natural barrier.

When you see histidine HCL on a label, it is typically added for its amino acid profile, contributing to a product's ability to hydrate and protect skin.

Commonly found in: body lotions, face creams, serums, hand creams

Benefits

  • Histidine plays a role in skin hydration and could help maintain the skin's natural barrier.
FDA

Histidine is generally recognized as safe (GRAS) for use in food and topical products.

Research

Research on topical applications of histidine HCL is limited, but it is recognized for its role in skin health and moisture retention.

Vegan

Histidine HCL is typically synthesized from non-animal sources, making it suitable for vegans.

Sources: Safety Assessment of Histidine and Its Salts as Used in Cosmetics

Scout's take

Histidine HCL is an amino acid used in skincare for its potential moisturizing properties. It may help improve skin hydration and elasticity. Its benefits in topical application are not well-established.

The case against

There are minimal risks, though it may cause irritation in very sensitive skin.

from the analysis of Eucerin Advanced Repair Lotion for Very Dry Skin Bottle

The case for

Histidine HCL may help improve skin hydration and elasticity.

from the analysis of Eucerin Advanced Repair Lotion for Very Dry Skin Bottle

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