Crest Pro-Health Clean Mint Toothpaste

Active anticavity/antigingivitis/antisensitivity. Fluoride is a developmental neurotoxicant per The Lancet (2014); chronic ingestion linked to fluorosis, lowered IQ (NTP 2024), and thyroid suppression.

Solvent base.

Humectant; safe.

Sugar alcohol humectant; non-cariogenic.

Gentle abrasive.

Strongly alkaline pH adjuster (also used as an industrial degreaser); can disrupt enamel pH balance and irritate soft tissue with repeated exposure.

Harsh anionic surfactant. Documented trigger for recurrent aphthous (canker) ulcers (Herlofson & Barkvoll 1996); strips protective oral mucin; common contact irritant.

Chelator/stabilizer; inert at typical concentrations.

Amino acid recently added to the formula for biofilm disruption. Marginal functional benefit but does not offset the systemic issues.

Proprietary flavor blend; can hide dozens of synthetic compounds and phthalate carriers under FDA trade-secret rules.

Secondary surfactant. American Contact Dermatitis Society Allergen of the Year 2004.

Tartar-control phosphate associated with enamel erosion and gum irritation; high systemic phosphate intake linked to kidney stress.

Seaweed-derived stabilizer; documented gut inflammation and IBD trigger (Tobacman 2001, Borthakur et al. 2007). No reason for it to be in a topical oral product.

Synthetic sweetener; gut microbiome disruption (Suez et al. 2014); historical NTP carcinogen listing.

Stabilizer for the stannous fluoride active.

Plant-derived thickener.

PEG thickener/solvent; commonly contaminated with 1,4-dioxane and ethylene oxide as ethoxylation byproducts.

Inert mineral colorant for shimmer.

EU food-additive ban (2022) over genotoxicity concerns from nanoparticles; IARC Group 2B.