Kirkland Signature Glucosamine with MSM 375 Tablets

Common questions

Is Kirkland Signature Glucosamine with MSM 375 Tablets healthy?

Kirkland Signature Glucosamine with MSM 375 Tablets scores 78/100 on Scout's independent analysis of ingredients, additives, and lab results — a fair-to-good score — solid, with tradeoffs. This supplement contains beneficial ingredients like Methylsulfonylmethane and Glucosamine Hydrochloride, which are known for supporting joint health.

How processed is Kirkland Signature Glucosamine with MSM 375 Tablets?

Kirkland Signature Glucosamine with MSM 375 Tablets is NOVA Group 3: Processed Foods.

Which ingredients drive Kirkland Signature Glucosamine with MSM 375 Tablets' score?

In Scout's ingredient-by-ingredient analysis, Methylsulfonylmethane, Glucosamine Hydrochloride count in its favor; Maltodextrin is flagged as an ingredient of concern. The full breakdown, with why each one matters, is in the Key ingredients section on this page.

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Kirkland Signature Glucosamine with MSM 375 Tablets

Kirkland
78 Good

Analysis updated July 2026 · How Scout scores

$40.62 · 375 count · pack of 2 · $0.05 / count
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At a glance

Beneficial ingredients 2
Harmful ingredients 1
Owned by Costco
Category Vitamins and Minerals
Summary

This supplement contains beneficial ingredients like Methylsulfonylmethane and Glucosamine Hydrochloride, which are known for supporting joint health. However, the presence of magnesium stearate, a common additive that may inhibit nutrient absorption, slightly detracts from its overall formulation quality. The product is moderately processed, but the inclusion of effective joint-supporting compounds contributes positively to its score.

Key ingredients 8

Methylsulfonylmethane
Good

Methylsulfonylmethane (MSM) is known for its anti-inflammatory properties and potential to support joint health. It is a naturally occurring compound that may help reduce joint pain and improve mobility. MSM is often used in supplements for its potential benefits in reducing inflammation and supporting connective tissue health.

Benefits

MSM may help reduce joint pain and inflammation, supporting overall joint health.

Glucosamine Hydrochloride
Good

Glucosamine Hydrochloride is a popular supplement ingredient for joint health, known to support cartilage formation and repair. It is often used to alleviate symptoms of osteoarthritis and improve joint function. This ingredient is valued for its role in maintaining healthy joints and reducing the progression of joint-related issues.

Benefits

Glucosamine Hydrochloride supports cartilage health and may reduce symptoms of osteoarthritis.

Cellulose Gel
Neutral

Cellulose Gel is a common filler and binder used in supplements to provide structure and consistency. It is derived from plant fibers and is generally considered safe for consumption. While it does not provide nutritional benefits, it is a neutral ingredient used for its functional properties in tablet formulation.

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Hypromellose
Neutral

Hypromellose is a cellulose-based polymer used as a coating agent and to control the release of active ingredients in supplements. It is widely used in the pharmaceutical industry for its stability and safety. This ingredient does not contribute to the nutritional profile but serves a functional role in supplement formulation.

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Stearic Acid
Neutral

Stearic Acid is a fatty acid used as a lubricant in supplement manufacturing to prevent ingredients from sticking to equipment. It is naturally found in many foods and is generally recognized as safe. While it does not offer nutritional benefits, it is a common and safe additive in supplements.

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Magnesium Stearate
Neutral

Standard formulation ingredient — neither beneficial nor harmful at typical use.

Risks

May inhibit the absorption of nutrients and reduce the bioavailability of active ingredients.

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Silicon Dioxide
Neutral

Silicon Dioxide is used as an anti-caking agent to prevent clumping in powdered supplements. It is a naturally occurring mineral and is considered safe for consumption. This ingredient does not contribute to the nutritional value but is important for maintaining product quality.

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Maltodextrin
Bad

Processed additive flagged under Scout's ingredient doctrine.

Benefits

Provides quick energy due to its rapid digestion.

See more about Maltodextrin →

Processing

Group 3 · Processed

Processed Foods

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