Life Extension Melatonin 6 Hour Timed Release 300 mcg extended-release formula for gentle sleep support healthy circadian rhythms cellular defense gluten-free non-GMO vegetarian 100 tablets
Analysis updated August 2026 · How Scout scores
At a glance
Summary
This melatonin supplement features a beneficial active ingredient known for supporting sleep quality and healthy circadian rhythms. However, the presence of several additives such as microcrystalline cellulose, hypromellose, and stearic acid indicates a moderate level of processing. While these additives are common in supplements, they slightly detract from the overall purity of the formulation.
Key ingredients 9
MelatoninGood
Melatonin is a hormone that regulates sleep-wake cycles and is beneficial for improving sleep quality. It is a high-quality active ingredient in sleep supplements, often used to support healthy circadian rhythms. Its effectiveness is well-documented, especially in timed-release formulations that mimic natural melatonin production.
Benefits
Supports sleep regulation and can help improve sleep onset and duration.
Microcrystalline CelluloseNeutral
Microcrystalline cellulose is a common filler and binder used in supplements to provide structure. It is generally considered safe and inert, with no significant health impacts. It does not contribute to the nutritional value of the product.
See more about Microcrystalline Cellulose →HypromelloseNeutral
Hypromellose is used as a coating agent and to control the release of active ingredients in supplements. It is a synthetic polymer that is generally recognized as safe. It does not provide nutritional benefits but aids in the timed-release mechanism.
Benefits
Facilitates controlled release of active ingredients, enhancing the effectiveness of the supplement.
Hydroxypropyl CelluloseNeutral
Hydroxypropyl cellulose is used as a thickener and stabilizer in supplements. It is a chemically modified cellulose that is considered safe for consumption. It does not add nutritional value but helps maintain the product's consistency.
See more about Hydroxypropyl Cellulose →Stearic AcidNeutral
Stearic acid is a fatty acid used as a lubricant in supplement manufacturing. It is naturally occurring and generally recognized as safe. It does not impact the nutritional profile of the product.
See more about Stearic Acid →Coating (Purified Water, Hypromellose, Glycerin)Neutral
The coating is used to protect the tablet and control the release of active ingredients. It consists of purified water, hypromellose, and glycerin, all of which are safe and commonly used in supplements. The coating does not contribute to the nutritional value but ensures product stability.
Benefits
Ensures stability and controlled release of the active ingredient.
Vegetable StearateNeutral
Vegetable stearate is used as a lubricant in supplement manufacturing to prevent ingredients from sticking to equipment. It is derived from vegetable oils and is generally recognized as safe. It does not provide nutritional benefits.
Croscarmellose SodiumNeutral
Croscarmellose sodium is a disintegrant used in tablets to help them dissolve properly. It is a cellulose derivative that is considered safe for consumption. It does not add nutritional value but aids in the tablet's effectiveness.
Benefits
Enhances the dissolution and absorption of the active ingredient.
SilicaNeutral
Silica is used as an anti-caking agent in supplements to prevent clumping. It is a naturally occurring mineral that is safe for consumption. It does not contribute to the nutritional profile of the product.
See more about Silica →Processing
Processed Foods
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