Pure Encapsulations O.N.E. Multivitamin - Once Daily Multivitamin with Antioxidant Complex Metafolin CoQ10 and Lutein to Support Vision Cognitive Function and Cellular Health* - 120 Capsules
Analysis updated August 2026 · How Scout scores
At a glance
Summary
This multivitamin features a comprehensive blend of essential vitamins and minerals in bioavailable forms, such as methylcobalamin for B12 and L-5MTHF for folate, which are known for their high absorption rates. The formulation includes beneficial antioxidants like CoQ10 and lutein, supporting vision and cognitive health. While it contains several additives, they are primarily benign, and the absence of harmful ingredients like artificial dyes or sweeteners contributes to its high rating.
Key ingredients 29
Vitamin CVery Good
Vitamin C is a powerful antioxidant that supports the immune system and skin health. Ascorbic acid is a highly bioavailable form of vitamin C. It also aids in the absorption of iron from plant-based foods.
Risks
High doses may cause gastrointestinal discomfort.
Benefits
Boosts immune function and enhances iron absorption.
Vitamin DVery Good
Vitamin D is crucial for bone health and immune function. Cholecalciferol (D3) is the most effective form for raising blood levels of vitamin D. It helps in calcium absorption and bone mineralization.
Risks
Excessive intake can lead to hypercalcemia, causing nausea and weakness.
Benefits
Supports bone health and immune function.
FolateVery Good
Folate is essential for DNA synthesis and cell division. L-5MTHF is a bioactive form that is readily utilized by the body. It is crucial for fetal development and reducing homocysteine levels.
Benefits
Supports DNA synthesis and fetal development.
Coenzyme Q10Very Good
Coenzyme Q10 is a powerful antioxidant that supports cellular energy production. It is provided as CoQ10 and MicroActive CoQ10 for enhanced absorption. CoQ10 is crucial for heart health and mitochondrial function.
Benefits
Supports heart health and energy production.
FloraGLO LuteinVery Good
Lutein is a carotenoid that supports eye health and vision. FloraGLO is a patented form known for its high bioavailability. It protects against oxidative stress and age-related eye conditions.
Benefits
Supports eye health and protects against oxidative stress.
ZeaxanthinVery Good
Zeaxanthin is a carotenoid that supports eye health and vision. It is often paired with lutein for synergistic effects. Zeaxanthin helps filter harmful blue light and supports macular health.
Benefits
Supports eye health and filters harmful blue light.
Vitamin AGood
Vitamin A is essential for maintaining healthy vision, immune function, and skin health. It is provided in the form of vitamin A acetate and beta carotene, which are well-absorbed and effective. This vitamin plays a crucial role in cellular communication and growth.
Risks
Excessive intake of vitamin A can lead to toxicity, causing liver damage and other health issues.
Benefits
Supports vision, immune function, and skin health.
Vitamin EGood
Vitamin E acts as an antioxidant, protecting cells from oxidative damage. D-alpha tocopherol succinate is a natural and effective form. It supports skin health and immune function.
Risks
High doses may interfere with blood clotting.
Benefits
Protects cells from oxidative damage and supports skin health.
ThiaminGood
Thiamin (Vitamin B1) is essential for energy metabolism and nerve function. Thiamin HCl is a stable and bioavailable form. It plays a critical role in carbohydrate metabolism.
Benefits
Supports energy metabolism and nerve function.
RiboflavinGood
Riboflavin (Vitamin B2) is important for energy production and cellular function. It is a water-soluble vitamin that is easily absorbed. Riboflavin also supports skin and eye health.
Benefits
Supports energy production and cellular function.
NiacinGood
Niacin (Vitamin B3) supports energy metabolism and DNA repair. Niacinamide is a form that does not cause flushing. It is important for skin health and cholesterol management.
Risks
High doses may cause liver damage and gastrointestinal issues.
Benefits
Supports energy metabolism and skin health.
Vitamin B6Good
Vitamin B6 is crucial for amino acid metabolism and neurotransmitter synthesis. Pyridoxine HCl and pyridoxal 5' phosphate are effective forms. It supports brain health and mood regulation.
Risks
Excessive intake can lead to nerve damage.
Benefits
Supports brain health and neurotransmitter synthesis.
Vitamin B12Good
Vitamin B12 is vital for nerve function and red blood cell formation. Methylcobalamin is a bioactive form that is easily absorbed. It is important for energy production and neurological health.
Benefits
Supports nerve function and energy production.
BiotinGood
Biotin (Vitamin B7) supports hair, skin, and nail health. It is a water-soluble vitamin that aids in fatty acid metabolism. Biotin is also important for energy production.
Benefits
Supports hair, skin, and nail health.
Pantothenic AcidGood
Pantothenic acid (Vitamin B5) is essential for synthesizing coenzyme A. Calcium pantothenate is a stable form used in supplements. It supports energy metabolism and hormone production.
Benefits
Supports energy metabolism and hormone production.
CholineGood
Choline is important for liver function and brain development. Choline bitartrate is a common form used in supplements. It supports cognitive function and lipid metabolism.
Risks
High doses may cause fishy body odor and gastrointestinal distress.
Benefits
Supports liver function and cognitive health.
IodineGood
Iodine is crucial for thyroid hormone production and metabolic regulation. Potassium iodide is a stable form used in supplements. It supports energy metabolism and cognitive function.
Risks
Excessive intake can lead to thyroid dysfunction.
Benefits
Supports thyroid health and energy metabolism.
ZincGood
Zinc is essential for immune function and wound healing. Zinc citrate is a bioavailable form used in supplements. It supports skin health and DNA synthesis.
Risks
High doses may cause nausea and interfere with copper absorption.
Benefits
Supports immune function and skin health.
SeleniumGood
Selenium is a powerful antioxidant that supports thyroid function. Selenomethionine is a highly absorbable form. It plays a role in DNA synthesis and reproductive health.
Risks
Excessive intake can lead to selenosis, causing hair loss and nail brittleness.
Benefits
Supports thyroid function and antioxidant defense.
ManganeseGood
Manganese is important for bone formation and energy metabolism. Manganese citrate is a bioavailable form used in supplements. It supports antioxidant defense and wound healing.
Risks
High doses may cause neurological issues.
Benefits
Supports bone health and energy metabolism.
ChromiumGood
Chromium is essential for macronutrient metabolism and insulin sensitivity. Chromium polynicotinate is a stable form used in supplements. It supports blood sugar regulation and lipid metabolism.
Benefits
Supports blood sugar regulation and insulin sensitivity.
MolybdenumGood
Molybdenum is important for enzyme function and detoxification. TRAACS molybdenum glycinate chelate is a bioavailable form. It supports sulfur metabolism and antioxidant defense.
Benefits
Supports enzyme function and detoxification.
BoronGood
Boron supports bone health and hormone regulation. Boron glycinate is a bioavailable form used in supplements. It plays a role in calcium metabolism and cognitive function.
Benefits
Supports bone health and hormone regulation.
InositolGood
Inositol supports cellular health and neurotransmitter function. It is a naturally occurring compound that aids in lipid metabolism. Inositol is important for mental health and insulin sensitivity.
Benefits
Supports mental health and cellular function.
Alpha Lipoic AcidGood
Alpha lipoic acid is an antioxidant that supports glucose metabolism. It is both water and fat-soluble, enhancing its effectiveness. It supports nerve health and detoxification processes.
Benefits
Supports glucose metabolism and antioxidant defense.
LycopeneGood
Lycopene is a powerful antioxidant that supports heart health. It is a carotenoid found in tomatoes and other red fruits. Lycopene helps reduce oxidative stress and supports prostate health.
Benefits
Supports heart health and reduces oxidative stress.
Ascorbyl PalmitateGood
Beneficial ingredient — whole-food or functional value in this product class.
Benefits
Acts as an antioxidant to preserve supplement stability.
Vegetarian CapsuleNeutral
The vegetarian capsule is made from cellulose and water, serving as a delivery medium for the active ingredients. It is hypoallergenic and suitable for vegetarians. The capsule does not contribute any significant nutritional value.
Benefits
Provides a hypoallergenic delivery medium for active ingredients.
Hypoallergenic Plant FiberNeutral
Hypoallergenic plant fiber, made from cellulose, is used as a filler and stabilizer. It is inert and does not affect the nutritional profile of the supplement. This ingredient is suitable for individuals with allergies.
Benefits
Acts as a filler and stabilizer without affecting nutritional value.
Processing
Ultra-Processed Foods
Get the full breakdown in the Scout appTake Scout shopping
Scan any product to see lab results, healthy alternatives, and your personalized analysis.
Download on theApp Store GET IT ONGoogle Play