Pure Encapsulations O.N.E. Multivitamin - Once Daily Multivitamin with Antioxidant Complex Metafolin CoQ10 and Lutein to Support Vision Cognitive Function and Cellular Health* - 60 Capsules
Analysis updated August 2026 · How Scout scores
At a glance
Summary
This multivitamin contains a comprehensive range of essential vitamins and minerals, including bioavailable forms like Metafolin and CoQ10, which support various aspects of health such as vision, cognitive function, and cellular health. The formulation is clean, with no artificial additives or harmful ingredients, and uses a vegetarian capsule, making it a high-quality choice for daily supplementation.
Key ingredients 30
Vitamin CVery Good
Vitamin C is a powerful antioxidant that supports the immune system and skin health. It is often sourced from ascorbic acid, which is highly bioavailable. This vitamin also aids in collagen synthesis and enhances iron absorption.
Risks
High doses may cause gastrointestinal discomfort.
Benefits
Boosts immune function and acts as an antioxidant.
Vitamin DVery Good
Vitamin D is crucial for bone health and immune function. It is often provided as D3 (cholecalciferol), which is more effective in raising blood levels than D2. This vitamin aids in calcium absorption and bone mineralization.
Risks
Excessive intake can lead to hypercalcemia, affecting heart and kidney function.
Benefits
Supports bone health and immune system.
FolateVery Good
Folate is essential for DNA synthesis and cell division. It is often provided as Metafolin (L-methylfolate), which is more bioavailable. This vitamin is crucial for fetal development and red blood cell formation.
Risks
High doses may mask vitamin B12 deficiency.
Benefits
Supports DNA synthesis and fetal development.
Coenzyme Q10Very Good
Coenzyme Q10 is a powerful antioxidant that supports cellular energy production. It is often provided in a sustained-release form for better absorption. This compound is crucial for heart health and mitochondrial function.
Benefits
Supports heart health and energy production.
FloraGLO LuteinVery Good
FloraGLO lutein is a high-quality carotenoid that supports eye health. It is derived from marigold flowers and is known for its bioavailability. This compound helps filter harmful blue light and supports visual function.
Benefits
Supports eye health and visual function.
Vitamin AGood
Vitamin A is essential for maintaining healthy vision, immune function, and skin health. It is typically derived from high-quality sources like beta-carotene or retinyl palmitate. This vitamin is crucial for cellular communication and growth.
Risks
Excessive intake can lead to toxicity, causing liver damage and other health issues.
Benefits
Supports vision, immune system, and skin health.
Vitamin EGood
Vitamin E acts as an antioxidant, protecting cells from oxidative damage. It is usually derived from natural sources like mixed tocopherols. This vitamin supports skin health and immune function.
Risks
High doses may interfere with blood clotting.
Benefits
Protects cells from oxidative stress and supports skin health.
ThiaminGood
Thiamin (Vitamin B1) is essential for energy metabolism and nerve function. It is typically sourced from thiamine hydrochloride or mononitrate. This vitamin plays a critical role in converting nutrients into energy.
Benefits
Supports energy metabolism and nerve function.
RiboflavinGood
Riboflavin (Vitamin B2) is important for energy production and cellular function. It is often sourced from riboflavin or riboflavin-5-phosphate. This vitamin helps in the breakdown of proteins, fats, and carbohydrates.
Benefits
Aids in energy production and cellular function.
NiacinGood
Niacin (Vitamin B3) supports energy metabolism and DNA repair. It is commonly provided as niacinamide or nicotinic acid. This vitamin is crucial for converting food into energy and maintaining healthy skin.
Risks
High doses can cause flushing and liver damage.
Benefits
Supports energy metabolism and skin health.
Vitamin B6Good
Vitamin B6 is vital for amino acid metabolism and neurotransmitter synthesis. It is usually sourced from pyridoxine hydrochloride. This vitamin supports brain health and immune function.
Risks
Excessive intake can lead to nerve damage.
Benefits
Supports brain health and immune function.
Vitamin B12Good
Vitamin B12 is crucial for nerve function and red blood cell formation. It is typically sourced from methylcobalamin or cyanocobalamin. This vitamin supports energy production and neurological health.
Benefits
Supports nerve function and energy production.
BiotinGood
Biotin (Vitamin B7) is important for carbohydrate and fat metabolism. It is often sourced from biotin or D-biotin. This vitamin supports healthy hair, skin, and nails.
Benefits
Supports metabolism and healthy hair, skin, and nails.
Pantothenic AcidGood
Pantothenic acid (Vitamin B5) is essential for synthesizing coenzyme A and energy production. It is typically sourced from calcium pantothenate. This vitamin supports adrenal function and the synthesis of neurotransmitters.
Benefits
Supports energy production and adrenal function.
IodineGood
Iodine is crucial for thyroid hormone production and metabolic regulation. It is often sourced from potassium iodide or seaweed. This mineral supports cognitive function and energy metabolism.
Risks
Excessive intake can lead to thyroid dysfunction.
Benefits
Supports thyroid health and metabolism.
ZincGood
Zinc is important for immune function and wound healing. It is typically sourced from zinc citrate or zinc gluconate. This mineral supports DNA synthesis and cellular repair.
Risks
High doses can cause nausea and interfere with copper absorption.
Benefits
Supports immune function and wound healing.
SeleniumGood
Selenium is a powerful antioxidant that supports thyroid function. It is often sourced from selenomethionine or sodium selenite. This mineral protects cells from oxidative damage and supports immune health.
Risks
Excessive intake can lead to selenosis, causing hair and nail loss.
Benefits
Acts as an antioxidant and supports thyroid health.
ManganeseGood
Manganese is essential for bone formation and energy metabolism. It is typically sourced from manganese sulfate or manganese gluconate. This mineral supports enzyme function and antioxidant defense.
Risks
High doses can cause neurological issues.
Benefits
Supports bone health and enzyme function.
ChromiumGood
Chromium is important for macronutrient metabolism and blood sugar regulation. It is often sourced from chromium picolinate or chromium chloride. This mineral enhances insulin action and supports glucose metabolism.
Benefits
Supports blood sugar regulation and metabolism.
MolybdenumGood
Molybdenum is essential for enzyme function and detoxification processes. It is typically sourced from sodium molybdate. This mineral supports the breakdown of sulfites and purines.
Benefits
Supports enzyme function and detoxification.
BoronGood
Beneficial ingredient — whole-food or functional value in this product class.
Risks
High doses can cause reproductive and developmental toxicity.
Benefits
May support bone health and hormone regulation.
CholineGood
Choline is vital for liver function and brain development. It is typically sourced from choline bitartrate or phosphatidylcholine. This nutrient supports neurotransmitter synthesis and lipid metabolism.
Risks
Excessive intake can cause fishy body odor and hypotension.
Benefits
Supports brain health and liver function.
InositolGood
Beneficial ingredient — whole-food or functional value in this product class.
Benefits
May support mental health and insulin sensitivity.
Alpha Lipoic AcidGood
Alpha lipoic acid is an antioxidant that supports glucose metabolism and nerve health. It is often used for its potential to regenerate other antioxidants. This compound may help reduce oxidative stress and improve insulin sensitivity.
Risks
High doses may cause gastrointestinal discomfort.
Benefits
Supports glucose metabolism and reduces oxidative stress.
ZeaxanthinGood
Zeaxanthin is a carotenoid that supports eye health and protects against oxidative damage. It is often found alongside lutein in supplements. This compound helps maintain healthy vision and may reduce the risk of age-related macular degeneration.
Benefits
Supports eye health and protects against oxidative damage.
LycopeneGood
Lycopene is a powerful antioxidant that supports heart health and may reduce cancer risk. It is typically sourced from tomatoes or other red fruits. This compound helps protect cells from oxidative damage and supports cardiovascular health.
Benefits
Supports heart health and reduces oxidative damage.
Ascorbyl PalmitateGood
Beneficial ingredient — whole-food or functional value in this product class.
Benefits
Acts as an antioxidant and preserves supplement freshness.
Vegetarian CapsuleNeutral
The vegetarian capsule is made from cellulose and water, providing a plant-based alternative to gelatin capsules. It is minimally processed and hypoallergenic. This capsule is suitable for vegetarians and vegans.
Benefits
Provides a plant-based, hypoallergenic capsule option.
Hypoallergenic Plant FiberNeutral
Hypoallergenic plant fiber, typically cellulose, is used as a filler or binder in supplements. It is minimally processed and does not contain common allergens. This ingredient helps maintain capsule integrity.
Benefits
Helps maintain capsule integrity without allergens.
Potato StarchNeutral
Potato starch is used as a filler or binder in supplements. It is minimally processed and provides a gluten-free option. This ingredient helps maintain the structure and consistency of capsules.
Benefits
Provides a gluten-free filler option for capsule consistency.
Processing
Unprocessed or Minimally Processed Foods
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